Adaptive Immunity

Meiosis

Note Packet

Lesson

Topic

Statement(s) and Objective(s)

Activities

1	Life Cycles	3.3.U2: The halving of the chromosomes number allows a sexual life cycle with fusion of gametes. Compare sexual and asexual life cycles. Explain why meiosis must occur as part of a sexual life cycle.	Life Cycle Notes When does meiosis happen? Sexual vs Asexual CFU
2	History	3.3.NOS: Making careful observations- meiosis was discovered by microscope examination of dividing germ-line cells. Discuss difficulties in microscopic examination of dividing cells. Describe the discovery of meiosis.	Discovery of meiosis notes A&B: Discovery of meiosis reading
3	Phases	3.3.U3: DNA is replicated before meiosis so that all chromosomes consist of two sister chromatids. State that DNA is replicated in interphase before meiosis. Given a diploid number (for example 2n=4), outline the movement and structure of DNA through the stages of meiosis. 10.1.U1: Chromosomes replicate in interphase before meiosis. Identify tetrad, bivalent, sister chromatids and non-sister chromatids in diagrams of replicated chromosomes. 3.3.U4: The early stages of meiosis involves pairing of homologous chromosomes and crossing over followed by condensation. List three events that occur in prophase 1 of meiosis. Define bivalent and synapsis. Outline the process and result of crossing over. 10.1.U5: Homologous chromosomes separate in meiosis I. Contrast meiosis I with meiosis II. 3.3.U6: Separation of pairs of homologous chromosomes in the first division of meiosis halves the chromosome number. Explain why meiosis I is a reductive division. State that cells are haploid at the end of meiosis I. 10.1.U7: Sister chromatids separate in meiosis II. Compare meiosis II with mitosis. 3.3.U1: One of diploid nucleus divides by meiosis to produce four haploid nuclei. Compare divisions of meiosis I and meiosis II. 3.3.S1: Drawing diagrams to show the stages of meiosis resulting in the formation of four haploid cells. Outline the events of prophase, metaphase, anaphase and telophase in meiosis I and meiosis II. Draw diagrams of cells in prophase, metaphase, anaphase and telophase in meiosis I and meiosis II.	Readings Overview readings What is meiosis reading Scitable mitosis, meiosis and inheritance Replication and Distribution of DNA... Meiosis drawing notes Notes drawings with descriptions Meiosis phases review Meiosis CFU Meiosis flip cards Review activity: meiosis roll the dice SHS meiosis dance A&B: Rigged game of tug-of-war Mitosis vs meiosis blank table MItosis vs Meiosis slips mitosis vs meiosis slides Mitosis vs meiosis key Mitosis vs meiosis rap
4	Crossing over	10.1.U2: Crossing over is the exchange of DNA material between nonsister homologous chromatids. State that crossing over occurs during prophase I. Define chiasmata. 10.1.U3: Chiasmata formation between non-sister chromatids can results in an exchange of alleles. State two consequences of chiasmata formation between non-sister chromatids. 10.1.S1: Drawing diagrams to show chiasmata formed by crossing over. Draw a diagram to illustrate the process and result of crossing over.	Crossing over slides (Jeff Shaddock) Crossing over handwritten notes Crossing over CFU Crossing over news article Crossing over of X and Y case study Crossing over of X and Y news article Meiosis, genetic recombination Genetic recombination
5	Independent Assortment	3.3.U5: Orientation of pairs of homologous chromosomes prior to separation is random. Describe the attachment of spindle microtubules to chromosomes during meiosis I. Describe random orientation of chromosomes during meiosis I. 10.1.U6: Independent assortment of genes is due to the random orientation of pairs of homologous chromosomes in meiosis 1. Describe random orientation and independent assortment. Given a parent cell genotype, determine the allele combinations that are possible in the gametes due to independent assortment and random orientation.	Vision learning: indep. Assortment Independent assortment notes Independent assortment handwritten 1 Independent assortment handwritten 2 Independent assortment handwritten 3 Independent assortment CFU Independent assortment of genes CFU Group review of independent assortment slides
6	Segregation of Alleles	3.4.U3: The alleles of each gene separate into different haploid daughter nuclei during meiosis. State the outcome of allele segregation during meiosis. 10.2.U1: Unlinked genes segregate independently as a result of meiosis. State the difference between independent assortment of genes and segregation of alleles. Describe segregation of alleles and independent assortment of unlinked genes in meiosis.	Segregation of alleles slides Segregation of alleles handwritten Segregation of alleles CFU
7	Sources of Variation	10.1.U4: Crossing over produces new combinations of alleles on the chromosomes of the haploid cells. Draw a diagram to illustrate the formation of new allele combinations as a result of crossing over. 3.3.U7: Crossing over and random orientation promotes genetic variation. Explain how meiosis leads to genetic variation in gametes. State that the number of chromosome combinations possible due to random orientation is 2n. 3.3.U8: Fusion of gametes from different parents promotes genetic variation Outline the role of fertilization as a source of genetic variation.	Variation slides Variation handwritten notes Sources of variation CFU
8	Modeling		Chromoseratops Original Lesson Directions Chromosomes Example of colored chromosomes Slides for students MEiosis in Three Acts Course Source Lesson Chromosome sequences Lesson slides Design of the lesson Example of model Stop Action Movies Best of nominees Peer scoring form Example videos
9	Nondisjunction	3.3.A1: Nondisjunction can cause Down syndrome and other chromosome abnormalities. Studies show the age of parents influences chances of non-disjunction. Define nondisjunction. State the result of nondisjunction. Describe the cause and symptoms of Down syndrome. Explain the relationship between parental age and chances of non-disjunction.	Nondisjunction notes Nondisjunction CFU Extension: parthenogenesis lesson (with slides)
10	Wrap Up and Review		Meiosis review slides for groups Final knowledge audit Kahoot Quizizz MItosis vs Meiosis Quizizz 1-pager